Arcturusfoundation.com
Publications

Publications Authored or Co-Authored by Hellmuth Hinz

Journal and Book Chapter Publications
  1. Butcher, J.A., Jr., Hinz, H.R., Parsons, E.J., Peyser, J. A Convenient Synthesis of 1,n-Bis (4-Chloromethylphenyl) Alkanes. Tet. Lett. 24 (48) 5481-5482, 1984.
  2. Butcher, J.A., Jr., Hinz, H.R., Tsou, N., Shah, S. Laser versus. The Lamp: Photochemistry of Long Chained Bis-dibenzyl Ketones.  Tet. Lett. 25 (48) 5483-5486, 1984.
  3. Butcher, J.A., Jr., Dutta, A.K., Hinz, H.R. Macrocyclic Paracyclophane Synthesis. Tet. Lett. 25 (48) 5487-5488, 1984.
  4. Hinz, H.R. and Kirley, T.  Lysine 480 is an Essential Residue in the Putative ATP Site of Lamb Kidney (Na,K)-ATPase-Identification of the Pyridoxal 5'-Diphospho-5'-Adenosine and Pyridoxal Phosphate Reactive Residue. J. Biol. Chem. 265 (10) 10260-10265, 1990.
  5. Giovanella, B.C., Hinz, H.R., Kozielski, A.J., Stehlin, J.S., Potmesil, M. Efficacy of Camptothecin Analogues in Metastatic Models of Human Cancer. Paper presented for publication at the Third Conference on DNA Topoisomerases in Therapy, October 1990, New York, NY. In press.
  6. Giovanella, B.C., Hinz, H.R., Kozielski, A.J., Stehlin, J.S., Potmesil, M. and Silber, R. Complete Growth Inhibition of Human Cancer Xenografts in Nude Mice by Treatment with 20-(S)-Camptothecin. Cancer Res. 51, 3052-3055, 1991.
  7. Pantazis, P., Hinz, H.R., Mendoza, J.T., Kozielski, A.J., Williams, L.J. and Stehlin, J.S. Complete Inhibition of Growth Followed by Death of Human Malignant Melanoma Cells In Vitro and Regression of Human Melanoma Xenografts in Immunodeficient Mice Induced by Camptothecins. Cancer Res. J52, 3980-3987, 1992.
  8. Pantazis, P., Early, J.A., Kozielski, A.J., Hinz, H.R. and Giovanella, B.C. Regression of Human Breast Carcinoma Tumors in Immunodeficient Mice Treated with 9-Nitrocamptothecin: Differential Response of Nontumorigenic and Tumorigenic Cells In Vitro. Cancer Res. 53, 1577-1582, 1993.
  9. Pantazis, P., Kozielski, A.J., Mendoza, J.T., Early, J.A., Hinz, H.R. and Giovanella, B.C.  Camptothecin Derivatives Induce Regression of Human Ovarian Carcinomas Grown in Nude Mice and Distinguish Between Non-Tumorigenic and Tumorigenic Cells In Vitro. Intl. J. Cancer 53, 863-871, 1993.
  10. Stehlin, J. S., Natelson, E. A., Hinz, H. R., Giovanella, B. C., De Ipolyi, P. D., Fehir, K. M., Trezona, T. P., Vardeman, D. M., Harris, N. J., Marcee, A. K., Kozielski, A. J. and Ruiz-Razura, A.  Phase I clinical trial and pharmacokinetics results with oral administration of 20(S)-camptothecin. (for The Stehlin Foundation for Cancer Research) In Camptothecins: New Anticancer Agents, Chapter 5, pages 59-65, 1995. CRC Press, Inc., FL 33431.
  11. Hinz, H. R., Harris, H. J., Natelson, E. and Giovanella, B. C. Pharmacokinetics of the in vivo andin vitro conversion of 9-nitro-20(S)-camptothecin to 9-amino-20(S)-camptothecin in human, dog and mouse. Cancer Research 54, 3096-3100, 1994.
  12. Giovanella, B. C., Stehlin, J. S., Hinz, H. R., Kozielski, A. J., Harris, N. J. and Vardeman, D. M..  Preclinical evaluation of the anticancer activity and toxicity of 9-nitro-20(S)-camptothecin (Rubitecan). International Journal of Oncology, 20, 81-88, 2002.